#Anti stroke herbs trial#

#Anti stroke herbs trial#

Authors accessed the data in the same manner, and had no special privileges to the data.Р вЂќР вЂЎunding: This work was supported by grants from the Ministry of Health and Welfare, Taiwan (MOHW107-TDU-B-212-123004) China Medical University Hospital (DMR-107-192) Stroke Biosignature Project, Academia Sinica, Taiwan (BM10701010021) Clinical Trial Consortium for Stroke, Ministry of Science and Technology, Taiwan (MOST 106-2321-B-039-005) Ministry of Science and Technology, Taiwan (MOST 106-2321-B-039-019) 'Chinese Medicine Research Center, China Medical UniversityР Р†Р вЂљРЎСљ from the Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education, Taiwan Tseng-Lien Lin Foundation, Taichung, Taiwan and Katsuzo and Kiyo Aoshima Memorial Funds, Japan. Interested researchers can obtain the data by contacting NHIRD at. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Р вЂќР’Вata Availability: The data underlying this study is from the National Health Insurance Research Database (NHIRD). Received: ApAccepted: AugPublished: September 7, 2018Р вЂќР’В¬opyright: Р вЂ™Р’В© 2018 Lai et al. PLoS ONE 13(9):Р вЂќР’В®ditor: Chao Qiu, Fudan University, CHINA Although the analysis are limited by a lack of analytic information regarding lifestyle patterns, biochemical profiles, and levels of PD severity in database, this population-based study suggest that CHM may be an complementary therapy to reduce the risk of stroke in PD patients.Р вЂќР’В¬itation: Lai C-Y, Chiang J-H, Lin J-G, Yen H-R, Tu C-H, Chen Y-H (2018) Chinese herbal medicine reduced the risk of stroke in patients with ParkinsonР Р†Р вЂљРІвЂћСћs disease: A population-based retrospective cohort study from Taiwan. The analysis on the prescription pattern of CHM revealed that Danshen is the most common single herb and Ma Zi Ren Wan is the most common herbal formula. The probability curve generated from our follow-up data showed that PD patients receiving CHM treatment had a decreased risk of stroke compared with those not receiving CHM treatment (P <0.001). In a multivariable Cox proportional hazard model adjusted for potential comorbidities, the incidence of stroke was lower among PD patients using CHM compared with non-CHM users (11.10 per 100 person-years vs 23.15 per 100 person-years Hazard ratio: 0.56 95% confidence interval: 0.44 to 0.72). Both cohorts were followed until the end of 2013 for the incidence of new-onset stroke. We matched 290 patients who received Chinese herbal medicine (CHM) by age, sex, year of CHM prescription, and year of PD diagnosis with 290 patients who did not use CHM as control.

Herein, we analyzed a cohort of 1,000,000 records from TaiwanР Р†Р вЂљРІвЂћСћs National Health Insurance Research Database for the period 1997Р Р†Р вЂљРІР‚Сљ2011, and identified 1,882 patients with new-onset PD. Traditional Chinese medicine (TCM) has long been used in Asia to treat stroke, but there are no large-scale clinical data to confirm its efficacy in protecting PD patients against stroke. ParkinsonР Р†Р вЂљРІвЂћСћs disease (PD) is associated with a significantly increased risk of stroke.